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The principal cytochrome P450 isoenzyme associated appears to become CYP2E1, with CYP1A2 and CYP3A4 as further pathways. About eighty five% of the oral dose seems from the urine inside of 24 hrs of administration, most as the glucuronide conjugate, with tiny amounts of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity info.Propulsiv